Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.67 |
| ▸ | HTR2C | P28335 | 10/20 | 0.67 |
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 9/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294011 | 0.84 | HTR6 (0.69) | HTR2AHTR2CHTR6HTR1ADRD2 | |
| SCHEMBL20970934 | 0.83 | HTR6 (0.71) | HTR2AHTR2CHTR6HTR1ADRD2 | |
| SCHEMBL29536604 | 0.83 | HTR6 (0.71) | HTR2AHTR2CHTR6HTR1ADRD2 | |
| Bromide SCHEMBL31253213 | 0.83 | HTR6 (0.67) | HTR2AHTR2CHTR6HTR1ADRD2 | |
| SCHEMBL30288465 | 0.81 | HTR2A (0.67) | HTR2AHTR2CHTR6HTR1ADRD2 | |
| SCHEMBL7645002 | 0.80 | HTR2A (1.00) | HTR2AHTR2CHTR6DRD2 | |
| SCHEMBL30288467 | 0.80 | HTR6 (0.48) | HTR2AHTR2CHTR6HTR1ADRD2 | |
| SCHEMBL27902947 | 0.78 | HTT (0.51) | HTR2AHTR2CHTR6DRD2TSHR | |
| SCHEMBL24243735 | 0.76 | HTR6 (0.66) | HTR2AHTR2CHTR6HTR1ADRD2 | |
| SCHEMBL14141474 | 0.75 | HTR6 (0.65) | HTR2AHTR2CHTR6HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146198-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | Psilera Inc. (US) | 2023-03-15 | — | — | EP | claimed |
| EP-4146198-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | Psilera Inc. (US) | 2023-03-15 | — | — | EP | disclosed |