Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 14/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318560 | 0.82 | PIK3C3 (0.54) | PIK3C3MTOR | |
| SCHEMBL7767952 | 0.82 | PIK3C3 (0.54) | PIK3C3MTOR | |
| SCHEMBL27320448 | 0.82 | PIK3C3 (0.54) | PIK3C3MTOR | |
| SCHEMBL30516424 | 0.81 | MTOR (0.52) | PIK3C3MTORPDCD1CD274CHEK1 | |
| SCHEMBL26515061 | 0.81 | PIK3C3 (0.50) | PIK3C3MTOR | |
| SCHEMBL21256945 | 0.81 | PIK3C3 (0.50) | PIK3C3MTOR | |
| SCHEMBL30516408 | 0.80 | PIK3CD (0.52) | PIK3C3MTORPDCD1CD274CHEK1 | |
| SCHEMBL25222723 | 0.79 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL24681517 | 0.79 | MTOR (0.50) | PIK3C3MTOR | |
| SCHEMBL22296387 | 0.79 | PIK3C3 (0.49) | PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761804-A | Substituted condensed heterocyclic compound, preparation method and application thereof | 上海安诺达生物科技有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116462674-A | Morpholinyl pyridone compounds | 思普瑞特生物科学公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116444510-A | Morpholinyl pyridone compounds | 思普瑞特生物科学公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-116283960-A | Substituted condensed heterocyclic compound, preparation method and application thereof | 上海安诺达生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111108102-B | Morpholinyl pyridone compounds | 思普瑞特生物科学公司 | 2023-04-28 | — | — | CN | disclosed |