Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | ATR | Q13535 | 14/20 | 0.51 |
| ▸ | ATRIP | Q8WXE1 | 12/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30386045 | 0.91 | PIK3C3 (0.46) | PIK3CDPIK3CAATRATRIPPIK3C3 | |
| SCHEMBL30386169 | 0.91 | PIK3C3 (0.46) | PIK3CDPIK3CAATRATRIPPIK3C3 | |
| SCHEMBL24453719 | 0.85 | PIK3CD (0.52) | PIK3CDPIK3CAATRATRIPPDCD1 | |
| SCHEMBL30288871 | 0.80 | PIK3C3 (0.52) | PIK3CAATRATRIPPIK3C3PDCD1 | |
| SCHEMBL28539901 | 0.79 | ATR (0.55) | PIK3CDPIK3CAATRATRIPPIK3C3 | |
| SCHEMBL2127456 | 0.79 | ATR (0.55) | PIK3CDPIK3CAATRATRIPPIK3C3 | |
| SCHEMBL28539899 | 0.79 | ATR (0.55) | PIK3CDPIK3CAATRATRIPPIK3C3 | |
| SCHEMBL29442179 | 0.79 | ATR (0.55) | PIK3CDPIK3CAATRATRIPPIK3C3 | |
| SCHEMBL29261326 | 0.77 | PIK3CA (0.51) | PIK3CDPIK3CAATRATRIPPDCD1 | |
| SCHEMBL30629341 | 0.77 | PIK3CD (0.58) | PIK3CDPIK3CAATRATRIPPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375712-A | Dimorpholine-substituted heterocyclic compound and medical application thereof | 上海辉启生物医药科技有限公司 | 2023-07-04 | — | — | CN | disclosed |