SCHEMBL302896

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL303569	0.87	LMNA (0.46)	LMNAHPGDKMT2AGAAHTT
	SCHEMBL1722966	0.85	LMNA (0.49)	LMNAHPGDKMT2AGAAHTT
	SCHEMBL301981	0.84	LMNA (0.47)	LMNAHPGDKMT2AGAAHTT
	SCHEMBL302305	0.84	LMNA (0.46)	LMNAHPGDKMT2AGAAHTT
	SCHEMBL303273	0.83	HPGD (0.48)	LMNAHPGDKMT2AGAAHTT
	SCHEMBL3378147	0.78	KMT2A (0.43)	LMNAHPGDKMT2AALDH1A1PDE2A
	SCHEMBL302980	0.77	NPC1 (0.48)	LMNAHPGDKMT2AGAAHTT
	SCHEMBL3376238	0.76	LMNA (0.50)	LMNAHPGDKMT2AALDH1A1NR1I2
	SCHEMBL1726565	0.75	KMT2A (0.42)	LMNAKMT2APDE2A
	SCHEMBL3378993	0.75	LMNA (0.48)	LMNAHPGDKMT2AGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.