SCHEMBL3378147

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL303569	0.91	LMNA (0.46)	KMT2AMEN1LMNAPDE2AHPGD
	SCHEMBL2211106	0.87	LMNA (0.48)	KMT2AMEN1LMNAHPGDFNTA
	SCHEMBL1726565	0.87	KMT2A (0.42)	KMT2AMEN1LMNAPDE2ASLC6A9
	SCHEMBL3376238	0.86	LMNA (0.50)	KMT2AMEN1LMNAHPGDPKM
	SCHEMBL3378993	0.85	LMNA (0.48)	KMT2AMEN1LMNAPDE2AHPGD
	SCHEMBL17075498	0.84	LMNA (0.45)	KMT2AMEN1LMNAHPGDFNTA
	SCHEMBL304694	0.81	LMNA (0.39)	KMT2AMEN1LMNAPDE2AHPGD
	SCHEMBL2212915	0.80	MEN1 (0.58)	KMT2AMEN1LMNAFNTAFNTB
	SCHEMBL3378334	0.80	KMT2A (0.45)	KMT2AMEN1LMNAHPGDPKM
	SCHEMBL3376397	0.79	KMT2A (0.50)	KMT2AMEN1LMNAHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.