Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289833 | 0.86 | MAPT (0.52) | MAPTKMT2AMEN1KDM4EMMP13 | |
| SCHEMBL30289860 | 0.81 | MAPT (0.45) | MAPTKMT2AMEN1KDM4EPARP1 | |
| SCHEMBL30289855 | 0.79 | MEN1 (0.60) | MAPTKMT2AMEN1KDM4ETP53 | |
| SCHEMBL30289873 | 0.76 | KDM4E (0.71) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL32666079 | 0.71 | KDM4E (0.67) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6930611 | 0.70 | RAB9A (0.48) | KMT2AMEN1KDM4EMMP13ALDH1A1 | |
| SCHEMBL30289868 | 0.70 | MAPT (0.52) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL30289853 | 0.70 | MAPT (0.48) | MAPTKMT2AMEN1KDM4EPARP1 | |
| SCHEMBL30289897 | 0.70 | KMT2A (0.75) | MAPTKMT2AMEN1KDM4EMMP13 | |
| SCHEMBL2004452 | 0.69 | MEN1 (0.60) | MAPTKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |