Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289844 | 0.86 | MAPT (0.52) | MAPTMEN1KMT2AKDM4EMMP13 | |
| SCHEMBL30289798 | 0.81 | MAPT (0.45) | MAPTMEN1KMT2AKDM4ETAAR1 | |
| SCHEMBL30289840 | 0.79 | MEN1 (0.53) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL30289854 | 0.76 | KDM4E (0.71) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL32666079 | 0.71 | KDM4E (0.67) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25338930 | 0.70 | ELANE (0.56) | MEN1KMT2AKDM4EMMP13ALDH1A1 | |
| SCHEMBL1996492 | 0.69 | MEN1 (0.60) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30289960 | 0.69 | MAPT (0.47) | MAPTMEN1KMT2AKDM4ETAAR1 | |
| SCHEMBL26438897 | 0.69 | ELANE (0.48) | KDM4EMMP13ALDH1A1HPGDPARP1 | |
| SCHEMBL30289911 | 0.69 | POLA1 (0.41) | MAPTMEN1KMT2AKDM4ETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |