Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.51 |
| ▸ | PRKDC | P78527 | 4/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.41 |
| ▸ | FLT1 | P17948 | 3/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289868 | 0.79 | MAPT (0.52) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30289949 | 0.76 | MAPT (0.52) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30289873 | 0.74 | KDM4E (0.71) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30289790 | 0.73 | MAPT (0.46) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30289858 | 0.72 | MAPT (0.49) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30289838 | 0.72 | RIPK1 (0.49) | MEN1KMT2AKDM4EMAPTCYP3A4 | |
| SCHEMBL4382248 | 0.72 | TTBK1 (0.56) | STAT3PIK3CAMEN1KMT2AMAPT | |
| SCHEMBL30289989 | 0.70 | MEN1 (0.45) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2924524 | 0.70 | PIK3CA (0.49) | STAT3PIK3CDPIK3CAPIK3CBPDE3B | |
| SCHEMBL23712415 | 0.69 | MAPK10 (0.50) | MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |