Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.54 |
| ▸ | ACE | P12821 | 4/20 | 0.52 |
| ▸ | CCKAR | P32238 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.50 |
| ▸ | ITGAL | P20701 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886730 | 0.98 | ERAP2 (0.54) | ERAP2ACECCKARCCKBROPRD1 | |
| SCHEMBL29886823 | 0.89 | ERAP2 (0.58) | ERAP2ACEOPRD1LTA4HECE1 | |
| SCHEMBL15757296 | 0.87 | ERAP2 (0.62) | ERAP2ACEP2RY14ALOX15ITGB2 | |
| SCHEMBL15757291 | 0.87 | ERAP2 (0.62) | ERAP2ACEP2RY14ALOX15ITGB2 | |
| SCHEMBL29352080 | 0.87 | ERAP2 (0.62) | ERAP2ACEP2RY14ALOX15ITGB2 | |
| SCHEMBL29366904 | 0.87 | ERAP2 (0.60) | ERAP2ACEOPRD1LTA4HECE1 | |
| SCHEMBL31593293 | 0.86 | ACE (0.53) | ACECCKARCCKBROPRD1LTA4H | |
| SCHEMBL30358212 | 0.86 | ACE (0.54) | ERAP2ACEOPRD1P2RY14ALOX15 | |
| SCHEMBL30503004 | 0.85 | LTA4H (0.60) | ACECCKARCCKBROPRD1LTA4H | |
| SCHEMBL24933037 | 0.84 | CTSL (0.57) | ACEOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355367-A1 | SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES FOR DRUG DELIVERY APPLICATIONS | Barinthus Biotherapeutics North America, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022266340-A1 | SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES FOR DRUG DELIVERY APPLICATIONS | VACCITECH NORTH AMERICA, INC. (US) | 2022-12-22 | — | — | WO | disclosed |