Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645060 | 1.00 | HDAC4 (0.39) | HDAC4OPRM1OPRL1HTR1ASLC6A2 | |
| SCHEMBL23644320 | 0.84 | OPRM1 (0.39) | HDAC4OPRM1OPRL1DPP4SIGMAR1 | |
| SCHEMBL30291422 | 0.84 | OPRM1 (0.39) | HDAC4OPRM1OPRL1DPP4SIGMAR1 | |
| SCHEMBL30291219 | 0.81 | HDAC4 (0.41) | HDAC4OPRM1OPRL1HTR1ASLC6A2 | |
| SCHEMBL23645494 | 0.81 | HDAC4 (0.41) | HDAC4OPRM1OPRL1HTR1ASLC6A2 | |
| SCHEMBL23644323 | 0.77 | HDAC4 (0.32) | HDAC4 | |
| SCHEMBL23645286 | 0.76 | OPRM1 (0.35) | HDAC4OPRM1OPRL1DPP4SIGMAR1 | |
| SCHEMBL30291320 | 0.76 | OPRM1 (0.41) | HDAC4OPRM1OPRL1DPP4SIGMAR1 | |
| SCHEMBL23668800 | 0.76 | OPRM1 (0.41) | HDAC4OPRM1OPRL1DPP4SIGMAR1 | |
| SCHEMBL23645522 | 0.75 | OPRM1 (0.40) | HDAC4OPRM1OPRL1DPP4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087700-B | Spirocyclic tetrahydroquinazolines | 苏州亚盛药业有限公司 | 2023-03-14 | — | — | CN | disclosed |