Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23668800 | 1.00 | OPRM1 (0.41) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL23645522 | 0.90 | OPRM1 (0.40) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL30291243 | 0.90 | OPRM1 (0.40) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL23645487 | 0.81 | OPRM1 (0.35) | OPRM1OPRL1DPP4SIGMAR1HDAC4 | |
| SCHEMBL23645211 | 0.81 | OPRM1 (0.35) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL30291422 | 0.80 | OPRM1 (0.39) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL23644320 | 0.80 | OPRM1 (0.39) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL23645063 | 0.79 | OPRM1 (0.38) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL23645212 | 0.79 | OPRM1 (0.33) | OPRM1OPRL1DPP4SIGMAR1EPHX2 | |
| SCHEMBL23645508 | 0.78 | SIGMAR1 (0.39) | OPRM1OPRL1DPP4SIGMAR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087700-B | Spirocyclic tetrahydroquinazolines | 苏州亚盛药业有限公司 | 2023-03-14 | — | — | CN | disclosed |