Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15644340 | 0.81 | SMN1; SMN2 (0.40) | NQO2FYNERN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16908272 | 0.81 | NQO2 (0.31) | NQO2FYNERN1 | |
| Hydrochloric Acid SCHEMBL15645074 | 0.80 | SMN1; SMN2 (0.39) | NQO2FYNERN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29882228 | 0.79 | DCPS (0.42) | PDE4APDE4D | |
| SCHEMBL3115217 | 0.76 | ALDH1A1 (0.51) | NQO2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL15645702 | 0.75 | MAPT (0.43) | ERN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30291339 | 0.75 | LATS1 (0.35) | — | |
| SCHEMBL16908229 | 0.71 | PIK3CB (0.48) | SMN1; SMN2 | |
| SCHEMBL17503773 | 0.71 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL17503802 | 0.71 | MAPT (0.46) | ERN1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900666-B1 | AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C | CANCER RESEARCH TECH LTD (GB) | 2020-11-04 | — | — | EP | disclosed |
| WO-2014052699-A9 | AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C | IGNYTA, INC. (US) | 2015-07-16 | — | — | WO | disclosed |