SCHEMBL30293265

SCHEMBL30293265

CC1CC(=O)Nc2ccc(O)cc21

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 9/20 0.57
CREBBP Q92793 9/20 0.57
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
ALDH1A1 P00352 1/20 0.41
EP300 Q09472 1/20 0.40
PDE3B Q13370 4/20 0.38
PDE3A Q14432 4/20 0.38
TP53 P04637 1/20 0.37
CYP19A1 P11511 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20715625 0.87 CREBBP (0.54) BRD4CREBBPMAOAMAOBEP300
SCHEMBL434946 0.81 BRD4 (0.53) BRD4CREBBPEP300TP53
SCHEMBL28978985 0.80 CREBBP (0.50) BRD4CREBBPMAOAMAOBALDH1A1
SCHEMBL30293263 0.80 CREBBP (0.50) BRD4CREBBPMAOAMAOBALDH1A1
SCHEMBL7264599 0.80 KMT2A (0.45) BRD4PDE3BPDE3ATP53
SCHEMBL17479629 0.80 CA9 (0.44) BRD4CREBBPALDH1A1EP300PDE3B
SCHEMBL9376059 0.78 BRD4 (0.47) BRD4CREBBPALDH1A1EP300
SCHEMBL10285196 0.78 MAOA (0.55) BRD4CREBBPMAOAMAOBALDH1A1
SCHEMBL21374146 0.78 BRD4 (0.44) BRD4CREBBPALDH1A1EP300PDE3B
SCHEMBL30293231 0.78 MAOA (0.55) BRD4CREBBPMAOAMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109988093-B Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine 广东东阳光药业有限公司 2023-04-07 CN disclosed