SCHEMBL30293274

SCHEMBL30293274

COC(=O)C1Cc2cc(OC)ccc2NC1=O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 2/20 0.49
PDE3A Q14432 2/20 0.49
ALDH1A1 P00352 2/20 0.42
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
SRC P12931 1/20 0.41
MTNR1A P48039 2/20 0.40
MTNR1B P49286 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30293234 1.00 PDE3B (0.49) PDE3BPDE3AALDH1A1GAATSHR
SCHEMBL7826091 0.88 PDE3B (0.50) PDE3BPDE3AALDH1A1GAATSHR
SCHEMBL7945190 0.87 ALDH1A1 (0.48) PDE3BPDE3AALDH1A1GAATSHR
SCHEMBL28978973 0.85 BRD4 (0.38) ALDH1A1MAOAMAOB
SCHEMBL7833042 0.84 PDE3B (0.47) PDE3BPDE3AALDH1A1SRCPOLB
SCHEMBL7945047 0.80 BRD4 (0.46) GAAMTNR1AMTNR1BMAPTMEN1
SCHEMBL30293258 0.80 BRD4 (0.46) GAAMTNR1AMTNR1BMAPTMEN1
SCHEMBL21061523 0.80 PDE3B (0.48) PDE3BPDE3AALDH1A1GAATSHR
Hydrochloric Acid SCHEMBL30293266 0.79 BRD4 (0.45) GAAMTNR1AMTNR1BMAPTMEN1
SCHEMBL4898004 0.77 PDE3B (0.54) PDE3BPDE3AALDH1A1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109988093-B Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine 广东东阳光药业有限公司 2023-04-07 CN disclosed