Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049209 | 0.90 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL30293274 | 0.87 | PDE3B (0.49) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL30293234 | 0.87 | PDE3B (0.49) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL7824596 | 0.84 | LMNA (0.53) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL7826091 | 0.83 | PDE3B (0.50) | ALDH1A1GAAHPGDHSD17B10MEN1 | |
| SCHEMBL10319302 | 0.82 | KDM4E (0.52) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL7078710 | 0.82 | PDE3B (0.42) | GAAHPGDKMT2AMAPTPDE3B | |
| SCHEMBL6197387 | 0.81 | ALOX15 (0.42) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL6197391 | 0.81 | ALOX15 (0.42) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL6197384 | 0.81 | ALOX15 (0.42) | ALDH1A1KDM4EGAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329389-B1 | HETEROCYCLIC AMINES AND DERIVATIVES, SOMATOSTATIN AND ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-11 | — | — | US | disclosed |