Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 14/20 | 0.47 |
| ▸ | CCND1 | P24385 | 14/20 | 0.47 |
| ▸ | CCND2 | P30279 | 10/20 | 0.47 |
| ▸ | CCND3 | P30281 | 10/20 | 0.47 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.47 |
| ▸ | CDK1 | P06493 | 3/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31475428 | 0.87 | CYP1A2 (0.50) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL28403699 | 0.80 | CDK4 (0.56) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL29611418 | 0.78 | CDK4 (0.54) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL28404489 | 0.78 | CDK4 (0.55) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL16248282 | 0.78 | CDK4 (0.54) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL13202803 | 0.78 | CDK4 (0.54) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL4826130 | 0.76 | CDK4 (0.52) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL29507845 | 0.76 | CDK4 (0.52) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL22553519 | 0.75 | CDK4 (0.52) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL13202797 | 0.75 | CDK4 (0.52) | CDK4CCND1CCND2CCND3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023035667-A1 | LOW-COST PREPARATION METHOD FOR PALBOCICLIB | 山东铂源药业股份有限公司 | 2023-03-16 | — | — | WO | disclosed |