SCHEMBL30294229

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.75

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	8/20	0.75

▸	GCGR	P47871	1/20	0.75

▸	GIPR	P48546	1/20	0.75

▸	CCKBR	P32239	1/20	0.73

▸	NR3C1	P04150	5/20	0.71

▸	IL23R	Q5VWK5	2/20	0.68

▸	PTH1R	Q03431	2/20	0.67

▸	ECE1	P42892	1/20	0.67

▸	MUS81	Q96NY9	1/20	0.67

▸	RXFP1	Q9HBX9	1/20	0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29383678	0.95	GLP1R (0.77)	GLP1RGCGRGIPRCCKBRNR3C1
SCHEMBL31279975	0.94	GLP1R (0.77)	GLP1RGCGRGIPRCCKBRNR3C1
SCHEMBL31182580	0.94	GLP1R (0.75)	GLP1RGCGRGIPRCCKBRNR3C1
SCHEMBL15268863	0.94	GLP1R (0.81)	GLP1RGCGRGIPRCCKBRNR3C1
SCHEMBL29354319	0.94	GLP1R (0.81)	GLP1RGCGRGIPRCCKBRNR3C1
SCHEMBL23721788	0.93	GLP1R (0.72)	GLP1RGCGRGIPRCCKBRNR3C1
SCHEMBL4755	0.93	GLP1R (0.72)	GLP1RGCGRGIPRCCKBRNR3C1
Hydrochloric Acid SCHEMBL29363528	0.93	GLP1R (0.80)	GLP1RGCGRGIPRCCKBRNR3C1
SCHEMBL29429591	0.93	GLP1R (0.76)	GLP1RGCGRGIPRCCKBRNR3C1
Glycine SCHEMBL9450801	0.93	GLP1R (0.72)	GLP1RGCGRGIPRCCKBRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-117881417-A	Therapeutic methods and devices	挪威科技大学	2024-04-12	—	—	CN	disclosed
CN-110357959-B	GCGR antibody, fusion protein of GCGR antibody and GLP-1, and pharmaceutical composition and application of GCGR antibody and fusion protein	鸿运华宁（杭州）生物医药有限公司	2023-02-28	—	—	CN	disclosed