Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.59 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.59 |
| ▸ | CDK9 | P50750 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | AXL | P30530 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587 | 1.00 | PIM1 (0.59) | PIM1HASPINCCNT1CDK9HTR6 | |
| SCHEMBL29814872 | 0.83 | PIM1 (0.59) | PIM1HASPINCCNT1CDK9AXL | |
| SCHEMBL1892610 | 0.83 | PIM1 (0.59) | PIM1HASPINCCNT1CDK9AXL | |
| SCHEMBL16168495 | 0.75 | HTR6 (0.56) | PIM1HASPINCCNT1CDK9HTR6 | |
| SCHEMBL2050489 | 0.75 | HASPIN (0.59) | PIM1HASPINCCNT1CDK9HTR6 | |
| SCHEMBL30067091 | 0.75 | HASPIN (0.59) | PIM1HASPINCCNT1CDK9HTR6 | |
| SCHEMBL14059758 | 0.75 | GSK3B (0.51) | PIM1HASPINCCNT1CDK9HTR6 | |
| SCHEMBL3224448 | 0.75 | ATM (0.52) | PIM1HASPINCCNT1CDK9HTR6 | |
| SCHEMBL29535106 | 0.75 | ATM (0.52) | PIM1HASPINCCNT1CDK9HTR6 | |
| SCHEMBL15634812 | 0.75 | GSK3B (0.48) | PIM1HASPINCCNT1CDK9AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026090330-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| WO-2024220891-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-113924301-B | Pyrazolopyrazine derivative compound, pharmaceutical composition and application thereof | 北京普祺医药科技股份有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4408850-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2024-08-07 | — | — | EP | disclosed |
| EP-4408849-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2024-08-07 | — | — | EP | disclosed |
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |
| WO-2023055912-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |
| WO-2023055920-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |