Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 3/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224448 | 1.00 | ATM (0.52) | ATMHTR6PIM1PIM3PIM2 | |
| SCHEMBL2619228 | 0.83 | DYRK1A (0.56) | ATMHTR6PIM1PIM3PIM2 | |
| SCHEMBL31692009 | 0.80 | ATM (0.48) | ATMHTR6PIM1PIM3PIM2 | |
| SCHEMBL30067091 | 0.75 | HASPIN (0.59) | HTR6PIM1ACHETDO2DYRK1A | |
| SCHEMBL14059758 | 0.75 | GSK3B (0.51) | HTR6PIM1ACHETDO2DYRK1A | |
| SCHEMBL30295197 | 0.75 | PIM1 (0.59) | HTR6PIM1ACHETDO2DYRK1A | |
| SCHEMBL2050489 | 0.75 | HASPIN (0.59) | HTR6PIM1ACHETDO2DYRK1A | |
| SCHEMBL10587 | 0.75 | PIM1 (0.59) | HTR6PIM1ACHETDO2DYRK1A | |
| SCHEMBL16168495 | 0.75 | HTR6 (0.56) | HTR6PIM1ACHEDYRK1AGSK3B | |
| SCHEMBL24556549 | 0.75 | KDM4C (0.47) | PIM1PIM3PIM2DYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
| EP-4225742-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | Enliven Therapeutics, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076975-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | ATM 407/4885HTR6 2272/4885PIM1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.