Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19320836 | 0.84 | BCAT2 (0.49) | BCAT2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL528444 | 0.83 | BCAT2 (0.55) | BCAT2LTB4R2MEN1KMT2AKDM4E | |
| SCHEMBL19325774 | 0.82 | BCAT2 (0.50) | BCAT2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL21796063 | 0.81 | TACR1 (0.38) | MEN1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL28339942 | 0.79 | BCAT2 (0.50) | BCAT2LTB4R2MEN1KMT2AKDM4E | |
| Ether SCHEMBL28852012 | 0.77 | TSHR (0.52) | BCAT2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2242560 | 0.76 | BCAT2 (0.55) | BCAT2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL28342495 | 0.76 | CYP3A4 (0.48) | BCAT2LTB4R2MEN1KMT2AKDM4E | |
| SCHEMBL30514077 | 0.75 | BCAT2 (0.74) | BCAT2KDM4EMAPTCYP3A4TSHR | |
| SCHEMBL210767 | 0.75 | BCAT2 (0.74) | BCAT2KDM4EMAPTCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |