SCHEMBL528444

SCHEMBL528444

CCc1ccccc1-c1ccccc1C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.55
FGFR1 P11362 1/20 0.46
FGFR2 P21802 1/20 0.46
FGFR4 P22455 1/20 0.46
FGFR3 P22607 1/20 0.46
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
SLC9A1 P19634 1/20 0.44
CSNK1A1 P48729 1/20 0.44
TYRO3 Q06418 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
LTB4R2 Q9NPC1 1/20 0.43
DPP4 P27487 1/20 0.43
MEN1 O00255 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28339942 0.87 BCAT2 (0.50) BCAT2FGFR1FGFR2FGFR4FGFR3
SCHEMBL4434798 0.86 BCAT2 (0.44) BCAT2FGFR1FGFR2FGFR4FGFR3
SCHEMBL2242560 0.85 BCAT2 (0.55) BCAT2KDM4EMAPTALDH1A1HPGD
SCHEMBL28342495 0.84 CYP3A4 (0.48) BCAT2KDM4EMAPTTSHRKEAP1
SCHEMBL6555382 0.84 MAPT (0.52) BCAT2FGFR1FGFR2FGFR4FGFR3
SCHEMBL162322 0.84 MAPT (0.52) BCAT2FGFR1FGFR2FGFR4FGFR3
SCHEMBL210767 0.83 BCAT2 (0.74) BCAT2KDM4EMAPTALDH1A1HPGD
SCHEMBL30514077 0.83 BCAT2 (0.74) BCAT2KDM4EMAPTALDH1A1HPGD
SCHEMBL30296002 0.83 BCAT2 (0.46) BCAT2KDM4EMAPTALDH1A1HPGD
SCHEMBL28342494 0.83 MEN1 (0.50) BCAT2MAPTLTB4R2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012014127-A1 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2012-02-02 WO claimed
CN-108699045-B Substituted 2-oxoimidazolyl carboxamides as pest control agents 拜耳作物科学股份公司 2021-02-12 CN disclosed
CN-110650628-A Trisubstituted silylheteroaryloxyquinolines and analogs thereof 拜耳公司 2020-01-03 CN disclosed
CN-110582484-A Trisubstituted silylmethylphenoxyquinolines and analogs thereof 拜耳公司 2019-12-17 CN disclosed
CN-107842706-B running-in method for reducing friction coefficient between metal friction pairs QILU UNIVERSITY OF TECHNOLOGY (CN) 2019-12-10 CN disclosed
CN-101341133-A Quinazoline derivatives, process for their preparation and their use as anti-cancer agents ASTRAZENECA AB (SE) 2009-01-07 CN disclosed
CN-100427483-C Anthranilic acid amide derivatives and their pharmaceutical use NOVARTIS AG (CH) 2008-10-22 CN disclosed
CN-101198604-A NPY antagonists, their preparation and use CEREP (FR) 2008-06-11 CN disclosed