Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 11/20 | 0.56 |
| ▸ | EDNRB | P24530 | 8/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321684 | 1.00 | EDNRA (0.56) | EDNRAEDNRBBRD4FBP1 | |
| SCHEMBL29280990 | 0.93 | EDNRA (0.50) | EDNRAEDNRBBRD4 | |
| SCHEMBL5529599 | 0.86 | EDNRA (0.63) | EDNRAEDNRBBRD4 | |
| SCHEMBL30171185 | 0.86 | EDNRA (0.63) | EDNRAEDNRBBRD4 | |
| SCHEMBL5330400 | 0.84 | EDNRA (0.56) | EDNRAEDNRBBRD4FBP1 | |
| SCHEMBL30844573 | 0.84 | EDNRA (0.56) | EDNRAEDNRBBRD4FBP1 | |
| SCHEMBL5324233 | 0.78 | EDNRA (0.56) | EDNRAEDNRBBRD4FBP1 | |
| SCHEMBL26688897 | 0.75 | EDNRA (0.63) | EDNRAEDNRB | |
| SCHEMBL30844532 | 0.74 | EDNRA (0.52) | EDNRAEDNRB | |
| SCHEMBL27419865 | 0.74 | EDNRA (0.52) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |