Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296375 | 0.80 | CHRNB2 (0.42) | SCN9ACA1CA2CA9CA6 | |
| SCHEMBL4279787 | 0.79 | CA1 (0.38) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL30295970 | 0.79 | CA1 (0.38) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL30296338 | 0.78 | CA1 (0.42) | SCN9AALOX5APFEN1CA1CA2 | |
| SCHEMBL30296069 | 0.76 | CA2 (0.40) | SCN9AALOX5APFEN1CA1CA2 | |
| SCHEMBL30296408 | 0.76 | CA2 (0.46) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL30295779 | 0.75 | EDNRB (0.38) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL1080972 | 0.73 | CA2 (0.61) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL9396637 | 0.73 | CA2 (0.48) | ALOX5APFEN1CA1CA2CA9 | |
| SCHEMBL30839681 | 0.73 | CA2 (0.44) | ALOX5APFEN1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |