Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296120 | 0.81 | CHRM2 (0.43) | GPR119CHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL4861150 | 0.72 | MEN1 (0.42) | GPR119HSD17B2MEN1ALDH1A1LMNA | |
| SCHEMBL4861156 | 0.72 | MEN1 (0.42) | GPR119HSD17B2MEN1ALDH1A1LMNA | |
| SCHEMBL23229317 | 0.70 | AGTR2 (0.45) | GPR119CHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL7247150 | 0.70 | CHRM2 (0.48) | GPR119CHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL31080086 | 0.70 | CHRM2 (0.50) | GPR119CHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL31080406 | 0.70 | CHRM2 (0.50) | GPR119CHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL31080245 | 0.70 | CHRM2 (0.50) | GPR119CHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL21124699 | 0.70 | CHRM2 (0.50) | GPR119CHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL31080149 | 0.70 | CHRM2 (0.50) | GPR119CHRM2CHRM1CHRM3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451080-A | Tricyclic GPR65 modulators | 帕蒂奥斯治疗有限公司 | 2024-08-06 | — | — | CN | disclosed |