Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620171 | 1.00 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL30296712 | 0.89 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL26620185 | 0.89 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL26620114 | 0.78 | SMN1; SMN2 (0.34) | NPC1 | |
| SCHEMBL30296745 | 0.78 | SMN1; SMN2 (0.34) | NPC1 | |
| SCHEMBL31275214 | 0.73 | NPC1 (0.33) | DGAT1NPC1 | |
| SCHEMBL31274136 | 0.73 | MAPT (0.35) | DGAT1NPC1 | |
| SCHEMBL30296721 | 0.72 | NPC1 (0.33) | DGAT1NPC1 | |
| SCHEMBL26620126 | 0.72 | NPC1 (0.33) | DGAT1NPC1 | |
| SCHEMBL30903068 | 0.70 | KCNJ5 (0.39) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4402143-A1 | SPIROCYCLIC COMPOUNDS | Astrazeneca AB (SE) | 2024-07-24 | — | — | EP | disclosed |
| CN-117916241-A | Spiro compounds | 阿斯利康(瑞典)有限公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023036974-A1 | SPIROCYCLIC COMPOUNDS | ASTRAZENECA AB (SE) | 2023-03-16 | — | — | WO | disclosed |