Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275360 | 0.89 | MAPT (0.33) | MAPTNPC1DGAT1 | |
| SCHEMBL24896337 | 0.81 | MAPT (0.38) | MAPTNPC1DGAT1F11 | |
| SCHEMBL31275214 | 0.79 | NPC1 (0.33) | MAPTNPC1DGAT1 | |
| SCHEMBL30220539 | 0.78 | NOD2 (0.38) | MAPTNPC1DGAT1 | |
| SCHEMBL31274986 | 0.77 | HRH3 (0.38) | RECQL | |
| SCHEMBL12489514 | 0.76 | NPC1 (0.39) | MAPTNPC1DGAT1 | |
| SCHEMBL21355498 | 0.76 | CYP19A1 (0.36) | MAPTNPC1F11 | |
| SCHEMBL30903098 | 0.75 | NPC1 (0.37) | MAPTNPC1 | |
| SCHEMBL17200345 | 0.74 | DGAT1 (0.37) | MAPTDGAT1 | |
| SCHEMBL30296703 | 0.73 | DGAT1 (0.34) | NPC1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255762-A1 | CBL-B INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2024-12-19 | — | — | WO | disclosed |