SCHEMBL30299016

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)O)C(C)C)[C@@H](C)O

nearest known ligand 0.69

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	5/20	0.69

▸	RAMP1	O60894	1/20	0.69

▸	RAMP2	O60895	1/20	0.69

▸	RAMP3	O60896	1/20	0.69

▸	CALCRL	Q16602	1/20	0.69

▸	CRHR1	P34998	1/20	0.64

▸	CRHR2	Q13324	1/20	0.64

▸	GLP1R	P43220	11/20	0.62

▸	CCKBR	P32239	2/20	0.62

▸	HCRTR1	O43613	1/20	0.61

▸	HCRTR2	O43614	1/20	0.61

▸	GCGR	P47871	9/20	0.60

▸	GIPR	P48546	6/20	0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29519841	0.97	CALCR (0.71)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL29720295	0.95	CALCR (0.73)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL2905167	0.95	CALCR (0.76)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL30063048	0.91	CALCR (0.75)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL29706213	0.91	CALCR (0.74)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL30252487	0.90	CALCR (0.60)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL29706332	0.90	CALCR (0.73)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL29908246	0.90	CALCR (0.74)	CALCRGLP1RCCKBRHCRTR1HCRTR2
SCHEMBL30598185	0.90	CALCR (0.74)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL31139952	0.89	CALCR (0.76)	CALCRCRHR1CRHR2GLP1RCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4144362-A1	COMPOSITIONS COMPRISING SHORT-ACTING HORMONES FOR TREATING OR PREVENTING OBESITY AND PUMPS COMPRISING SAID COMPOSITION	Adocia (FR)	2023-03-08	—	—	EP	disclosed