SCHEMBL30252487

CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)O)C(C)C

nearest known ligand 0.66

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	5/20	0.60

▸	RAMP1	O60894	1/20	0.59

▸	RAMP2	O60895	1/20	0.59

▸	RAMP3	O60896	1/20	0.59

▸	CALCRL	Q16602	1/20	0.59

▸	GLP1R	P43220	3/20	0.57

▸	GCGR	P47871	3/20	0.57

▸	CRHR1	P34998	1/20	0.55

▸	CRHR2	Q13324	1/20	0.55

▸	APLNR	P35414	2/20	0.54

▸	MC4R	P32245	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30299016	0.90	CALCR (0.69)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL29849478	0.89	MC4R (0.60)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL31255131	0.88	MC4R (0.64)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL2905167	0.88	CALCR (0.76)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL30429454	0.88	CALCR (0.62)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL29721233	0.87	APLNR (0.57)	CALCRGLP1RCRHR1CRHR2APLNR
SCHEMBL29707431	0.87	MC4R (0.62)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL31167610	0.87	CALCR (0.71)	CALCRGLP1RGCGR
SCHEMBL31182797	0.86	CALCR (0.70)	CALCRGLP1RGCGRCRHR1CRHR2
SCHEMBL31182896	0.86	CALCR (0.66)	CALCRGLP1RGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12083164-B2	Amylin analogues	ZEALAND PHARMA A/S (DK)	2024-09-10	—	—	US	disclosed
EP-4129324-A1	COMPOSITIONS COMPRISING AT LEAST AN AMYLIN RECEPTOR AGONIST AND A GLP-1 RECEPTOR AGONIST	Adocia (FR)	2023-02-08	—	—	EP	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-12083164-B2	Amylin analogues	IAPP, GLP1R, AMY2A	CALCR 532/4885RAMP1 1440/4885RAMP2 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.