Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19198139 | 1.00 | MEN1 (0.45) | MEN1USP2KMT2ARAB9AP2RX7 | |
| SCHEMBL19198145 | 0.72 | MEN1 (0.62) | MEN1USP2KMT2ARAB9AP2RX7 | |
| SCHEMBL6778508 | 0.71 | GBA1 (0.51) | RAB9ACYP3A4CYP2D6CYP2C9SMN1; SMN2 | |
| SCHEMBL8623490 | 0.70 | KDM4E (0.39) | MEN1KMT2AP2RX7EPHX2CYP3A4 | |
| Hydrochloric Acid SCHEMBL21641310 | 0.70 | CYP3A4 (0.44) | RAB9ACYP3A4CYP2D6CYP2C9GRIN2B | |
| SCHEMBL4037864 | 0.69 | KCNH3 (0.56) | RAB9ACYP3A4CYP2D6CYP2C9GRIN2B | |
| SCHEMBL12531359 | 0.69 | KDM1A (0.50) | RAB9ACYP3A4CYP2D6CYP2C9GRIN2B | |
| SCHEMBL3363335 | 0.69 | SMN1; SMN2 (0.65) | P2RX7CYP2D6SMN1; SMN2LTA4HCYP1A2 | |
| SCHEMBL13493771 | 0.69 | CYP3A4 (0.49) | KMT2ARAB9ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20724728 | 0.68 | EPHX2 (0.60) | MEN1USP2KMT2ARAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2023-09-14 | — | — | US | disclosed |
| US-11639333-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC (US) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM5A, KDM1A | MEN1 1315/4885USP2 485/4885KMT2A 45/4885 |
| US-11639333-B2 | Histone demethylase inhibitors | KDM1B, KDM5A, KDM1A | MEN1 1315/4885USP2 485/4885KMT2A 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.