Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778508 | 0.84 | GBA1 (0.51) | CYP3A4CYP2D6CYP2C9GRIN2BCRHR1 | |
| SCHEMBL6688393 | 0.82 | KCNH3 (0.42) | KCNH3FYNKDRCRHR1RAB9A | |
| SCHEMBL13493771 | 0.81 | CYP3A4 (0.49) | CYP3A4CYP2D6CYP2C9GRIN2BCRHR1 | |
| SCHEMBL12531359 | 0.81 | KDM1A (0.50) | CYP3A4CYP2D6CYP2C9GRIN2BCRHR1 | |
| SCHEMBL5793778 | 0.80 | KCNH3 (0.65) | KCNH3KDRCRHR1RAB9ACNR2 | |
| SCHEMBL6692757 | 0.80 | HTR5A (0.44) | KCNH3FYNCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29937887 | 0.76 | FYN (0.50) | KCNH3FYNKCNH2ATMATR | |
| Hydrochloric Acid SCHEMBL21641310 | 0.76 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP2C9GRIN2BCRHR1 | |
| SCHEMBL21207114 | 0.74 | KCNH3 (0.45) | KCNH3KDRCNR2CCNT1CDK9 | |
| SCHEMBL1462718 | 0.74 | CCNT1 (0.47) | KCNH3FYNCYP2D6CYP2C9KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555265-B1 | 7-PHENYL PYRAZOLOPYRIDINE COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2009-03-25 | — | — | EP | claimed |