Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.59 |
| ▸ | ANPEP | P15144 | 3/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | REN | P00797 | 2/20 | 0.57 |
| ▸ | NTSR2 | O95665 | 5/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | DPP3 | Q9NY33 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434308 | 0.93 | LNPEP (0.59) | LNPEPANPEPSLC6A2RENAGTR1 | |
| SCHEMBL11782844 | 0.92 | LNPEP (0.64) | LNPEPANPEPSLC6A2RENNTSR2 | |
| SCHEMBL31121210 | 0.92 | LNPEP (0.66) | LNPEPANPEPSLC6A2RENAGTR1 | |
| SCHEMBL11782852 | 0.92 | LNPEP (0.64) | LNPEPANPEPSLC6A2RENNTSR2 | |
| SCHEMBL31356485 | 0.89 | ANPEP (0.64) | LNPEPANPEPSLC6A2NTSR2NTSR1 | |
| SCHEMBL29607899 | 0.89 | SLC6A2 (0.61) | LNPEPANPEPSLC6A2RENNTSR2 | |
| SCHEMBL29392664 | 0.88 | LNPEP (0.65) | LNPEPANPEPSLC6A2RENNTSR2 | |
| SCHEMBL30695688 | 0.88 | SLC6A2 (0.55) | LNPEPANPEPSLC6A2RENXIAP | |
| SCHEMBL29607543 | 0.87 | REN (0.63) | LNPEPANPEPSLC6A2RENNTSR2 | |
| SCHEMBL30400752 | 0.87 | NTSR2 (0.60) | LNPEPANPEPSLC6A2NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11597778-B2 | Human monoclonal autoantibodies to ADAMTS13 and uses thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-03-07 | — | — | US | disclosed |