Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299359 | 0.76 | CYP2C9 (0.35) | LMNAKMT2AMAPTL3MBTL1 | |
| SCHEMBL30299382 | 0.76 | — | — | |
| SCHEMBL15450782 | 0.76 | HTT (0.42) | HSD11B1LMNASMN1; SMN2KMT2AMKNK1 | |
| SCHEMBL30299292 | 0.73 | HRH3 (0.32) | — | |
| SCHEMBL10202552 | 0.72 | LMNA (0.45) | HSD11B1LMNASMN1; SMN2KMT2AMKNK1 | |
| SCHEMBL13262126 | 0.72 | MAPT (0.40) | HSD11B1LMNASMN1; SMN2KMT2AMKNK1 | |
| SCHEMBL27790982 | 0.71 | MAPT (0.37) | HSD11B1LMNASMN1; SMN2KMT2AMKNK1 | |
| SCHEMBL30299333 | 0.70 | MAP3K14 (0.33) | — | |
| SCHEMBL14853321 | 0.68 | HPGD (0.40) | LMNASMN1; SMN2KMT2AHTTMAPT | |
| SCHEMBL30299262 | 0.65 | HRH4 (0.39) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |