⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299292 | 0.93 | HRH3 (0.32) | — | |
| SCHEMBL30299333 | 0.81 | MAP3K14 (0.33) | — | |
| SCHEMBL30299359 | 0.77 | CYP2C9 (0.35) | — | |
| SCHEMBL30299384 | 0.76 | HSD11B1 (0.33) | — | |
| SCHEMBL30276325 | 0.76 | AXL (0.36) | — | |
| SCHEMBL30299383 | 0.74 | HRH3 (0.37) | — | |
| SCHEMBL30299340 | 0.74 | OPRK1 (0.37) | — | |
| SCHEMBL14853339 | 0.70 | FYN (0.38) | — | |
| SCHEMBL30299323 | 0.69 | NPY2R (0.41) | — | |
| SCHEMBL30299283 | 0.68 | L3MBTL3 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |