Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.31 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29928562 | 0.80 | CDK4 (0.31) | CDK4CCND1CDK2JAK2 | |
| SCHEMBL15652273 | 0.77 | MAP4K4 (0.42) | MAP4K4TLR7MCHR1HRH4HRH3 | |
| SCHEMBL30299360 | 0.77 | LRRK2 (0.39) | CDK4CCND1CDK2 | |
| SCHEMBL30299262 | 0.76 | HRH4 (0.39) | MAP4K4HRH4HRH3 | |
| SCHEMBL30299330 | 0.76 | GAA (0.34) | CHIT1CHIA | |
| SCHEMBL30299385 | 0.76 | KCNH2 (0.37) | HRH3 | |
| SCHEMBL30299316 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL30299346 | 0.75 | RET (0.36) | — | |
| SCHEMBL14853404 | 0.73 | PDE10A (0.45) | MAP4K4TLR7MCHR1JAK2HRH3 | |
| SCHEMBL10263545 | 0.72 | MCHR1 (0.46) | MAP4K4TLR7MCHR1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |