Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 7/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299262 | 0.89 | HRH4 (0.39) | HRH3 | |
| SCHEMBL30299373 | 0.85 | HRH3 (0.37) | HRH3 | |
| SCHEMBL30090686 | 0.80 | EML4 (0.39) | KCNH2FGFR3ACVR1ALK | |
| SCHEMBL30299362 | 0.80 | GPR4 (0.33) | — | |
| SCHEMBL30090486 | 0.80 | KCNH2 (0.39) | KCNH2FGFR3ACVR1ALK | |
| SCHEMBL30299346 | 0.77 | RET (0.36) | — | |
| SCHEMBL30299383 | 0.76 | HRH3 (0.37) | KCNH2HRH3 | |
| SCHEMBL10126760 | 0.76 | GRIN2D (0.46) | KCNH2FGFR3ACVR1HRH3 | |
| SCHEMBL30299403 | 0.76 | MAP4K4 (0.34) | HRH3 | |
| SCHEMBL30299283 | 0.74 | L3MBTL3 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |