Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14252696 | 0.87 | CYP2C19 (0.60) | CYP2C19HTTPOLBTACR3ALDH1A1 | |
| SCHEMBL8354032 | 0.83 | POLB (0.48) | CYP2C19HTTPOLBHDAC3HDAC1 | |
| SCHEMBL10157141 | 0.82 | HTT (0.43) | CYP2C19HTTHDAC3HDAC1HDAC2 | |
| SCHEMBL21162019 | 0.81 | POLB (0.47) | CYP2C19HTTPOLBALDH1A1KDM4E | |
| SCHEMBL1697725 | 0.81 | CYP1A2 (0.47) | CYP2C19HTTPOLBHDAC3HDAC1 | |
| SCHEMBL5988502 | 0.81 | POLB (0.47) | CYP2C19HTTPOLBALDH1A1KDM4E | |
| SCHEMBL5987740 | 0.81 | POLB (0.65) | HTTPOLBHDAC3HDAC1HDAC2 | |
| SCHEMBL23112572 | 0.80 | CYP2C19 (0.54) | CYP2C19HTTPOLBTACR3ALDH1A1 | |
| SCHEMBL5988385 | 0.79 | POLB (0.44) | CYP2C19HTTPOLBALDH1A1KDM4E | |
| SCHEMBL28540955 | 0.79 | BCL2L1 (0.44) | CYP2C19HTTHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383863-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | INSTITUTE FOR BASIC SCIENCE (KR) | 2024-11-21 | — | — | US | disclosed |
| WO-2023043292-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | 기초과학연구원 | 2023-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383863-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | NUDT1, UMPS, DPYD | CYP2C19 1453/4885HTT 3577/4885POLB 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.