(+)-Epitaxifolin

(+)-Epitaxifolin

SCHEMBL30300560

O=C1c2c(O)cc(O)cc2O[C@@H](c2ccc(O)c(O)c2)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 4/20 1.00
▸ ALOX15 P16050 4/20 1.00
▸ MAPT P10636 3/20 1.00
▸ HSD17B10 Q99714 3/20 1.00
▸ RECQL P46063 2/20 1.00
▸ SOST Q9BQB4 2/20 1.00
▸ MEN1 O00255 2/20 1.00
▸ KMT2A Q03164 2/20 1.00
▸ KDM4E B2RXH2 2/20 1.00
▸ GAA P10253 2/20 1.00
▸ ALOX12 P18054 2/20 1.00
▸ HIF1A Q16665 2/20 1.00
▸ POLB P06746 1/20 1.00
▸ CYP1A2 P05177 1/20 1.00
▸ NFKB1 P19838 1/20 1.00
▸ MAPK1 P28482 1/20 1.00
▸ SYNJ2 O15056 3/20 0.75
▸ APP P05067 1/20 0.75
▸ XDH P47989 2/20 0.67
▸ IDO1 P14902 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taxifolin SCHEMBL29390633 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL30300501 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL30631315 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Epitaxifolin SCHEMBL31575455 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL29361519 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL13241264 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL29368246 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL1707803 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL7628142 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL296323 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023069981-A1 USES OF TAXIFOLIN FOR RESPIRATORY HEALTH PHYTO TECH CORP. (US) 2023-04-27 — — WO disclosed
WO-2023028586-A1 USE OF TAXIFOLIN FOR TREATING SYSTEMIC LUPUS ERYTHEMATOSUS PHYTO TECH CORP. (US) 2023-03-02 — — WO disclosed
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