Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076756 | 1.00 | CCR2 (0.66) | CCR2ADRA1AACHEHTR2AHTR7 | |
| SCHEMBL11879694 | 0.86 | CCR2 (0.75) | CCR2ADRA1AHTR2AHTR7DRD2 | |
| SCHEMBL11878825 | 0.84 | CCR2 (0.70) | CCR2ADRA1ADRD2 | |
| SCHEMBL25759383 | 0.82 | KCNA5 (0.61) | CCR2HTR2AHTR7DRD2KCNH2 | |
| SCHEMBL30376202 | 0.82 | KCNA5 (0.61) | CCR2HTR2AHTR7DRD2KCNH2 | |
| SCHEMBL6779774 | 0.81 | HRH2 (0.59) | CCR2ADRA1D | |
| SCHEMBL11879154 | 0.81 | CCR2 (0.77) | CCR2DRD2ADRA1D | |
| Succinic Acid SCHEMBL11876332 | 0.80 | CCR2 (0.68) | CCR2ADRA1ADRD2 | |
| SCHEMBL25759431 | 0.80 | KCNA5 (0.60) | CCR2HTR2AHTR7DRD2KCNH2 | |
| SCHEMBL30375766 | 0.80 | KCNA5 (0.60) | CCR2HTR2AHTR7DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4159725-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |