SCHEMBL25759431

SCHEMBL25759431

CCCCOc1ccc(S(=O)(=O)NCCCN2CCC(c3c[nH]c4ccccc34)CC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 2/20 0.60
KCNH2 Q12809 2/20 0.60
SLC2A1 P11166 1/20 0.53
ADRA1D P25100 4/20 0.52
SLC6A4 P31645 1/20 0.51
CCR2 P41597 1/20 0.49
DRD2 P14416 1/20 0.49
HTR2A P28223 1/20 0.49
HTR7 P34969 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30375766 1.00 KCNA5 (0.60) KCNA5KCNH2SLC2A1ADRA1DSLC6A4
SCHEMBL25759383 0.96 KCNA5 (0.61) KCNA5KCNH2SLC2A1ADRA1DSLC6A4
SCHEMBL30376202 0.96 KCNA5 (0.61) KCNA5KCNH2SLC2A1ADRA1DSLC6A4
SCHEMBL30375994 0.85 KCNA5 (0.49) KCNA5KCNH2SLC2A1SLC6A4DRD2
SCHEMBL25759401 0.85 KCNA5 (0.49) KCNA5KCNH2SLC2A1SLC6A4DRD2
SCHEMBL30375406 0.85 SLC6A4 (0.53) KCNA5KCNH2SLC6A4CCR2DRD2
SCHEMBL25758322 0.85 SLC6A4 (0.53) KCNA5KCNH2SLC6A4CCR2DRD2
SCHEMBL25286043 0.83 ADRA1D (0.50) KCNH2SLC2A1ADRA1DSLC6A4CCR2
SCHEMBL25252905 0.82 TSHR (0.54) KCNA5KCNH2SLC2A1ADRA1DDRD2
SCHEMBL24076756 0.80 CCR2 (0.66) KCNH2ADRA1DCCR2DRD2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157124-A Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-23 CN claimed
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 US disclosed
CN-116157124-A Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS SLC6A2, SLC6A3, SLC6A4 KCNA5 652/4885KCNH2 1959/4885SLC2A1 2321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.