Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | EYA2 | O00167 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL28302111 | 1.00 | GSR (0.67) | GSRTDP1EYA2APPACE | |
| Pentetic Acid SCHEMBL7885826 | 0.97 | GSR (0.67) | GSRTDP1EYA2APPACE | |
| Edetic Acid SCHEMBL4385387 | 0.93 | GSR (0.60) | GSRTDP1EYA2APPACE | |
| Edetic Acid SCHEMBL4385396 | 0.93 | GSR (0.60) | GSRTDP1EYA2APPACE | |
| Nitrilotriacetic Acid SCHEMBL4200594 | 0.91 | GSR (0.74) | GSRARG2BLMTSHRCYP2C19 | |
| SCHEMBL5613110 | 0.86 | TDP1 (0.50) | GSRTDP1EYA2APPACE | |
| SCHEMBL2305699 | 0.86 | GSR (0.53) | GSRTDP1EYA2APPACE | |
| SCHEMBL158633 | 0.86 | GSR (0.53) | GSRTDP1EYA2APPACE | |
| SCHEMBL10088294 | 0.84 | GSR (0.52) | GSRTDP1EYA2APPACE | |
| Water SCHEMBL1336386 | 0.84 | GSR (0.52) | GSRTDP1EYA2APPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819803-A | Self-healing collagen hydrogel material and preparation method thereof | 深圳钧兴生物科技有限公司 | 2023-03-21 | — | — | CN | disclosed |