Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | EYA2 | O00167 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158633 | 0.96 | GSR (0.53) | TDP1GSREYA2APPACE | |
| SCHEMBL2305699 | 0.96 | GSR (0.53) | TDP1GSREYA2APPACE | |
| Water SCHEMBL1336386 | 0.95 | GSR (0.52) | TDP1GSREYA2APPACE | |
| SCHEMBL10088294 | 0.95 | GSR (0.52) | TDP1GSREYA2APPACE | |
| SCHEMBL7166178 | 0.95 | GSR (0.52) | TDP1GSREYA2APPACE | |
| SCHEMBL10088295 | 0.91 | NOS2 (0.51) | TDP1GSREYA2APPACE | |
| SCHEMBL17690553 | 0.88 | GSR (0.46) | TDP1GSREYA2APPACE | |
| Edetic Acid SCHEMBL30301418 | 0.86 | GSR (0.67) | TDP1GSREYA2APPACE | |
| Pentetic Acid SCHEMBL7885826 | 0.86 | GSR (0.67) | TDP1GSREYA2APPACE | |
| SCHEMBL13233386 | 0.86 | GSR (0.47) | GSRTSHRCYP2C19BLMARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796738-A2 | DIAGNOSTIC COMPOUNDS FOR TARGETING A CHEMOKINE RECEPTOR | GUERBET (FR) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006032704-A2 | DIAGNOSTIC COMPOUNDS FOR TARGETING A CHEMOKINE RECEPTOR | GUERBET (FR) | 2006-03-30 | — | — | WO | disclosed |
| EP-0760683-B1 | BILE ACID CONJUGATES, DERIVATIVES THEREOF WITH METAL COMPLEXES AND RELATED USES | BRACCO SPA (IT) | 2000-01-05 | — | — | EP | disclosed |