SCHEMBL30302192

SCHEMBL30302192

Cc1ccc(S(=O)(=O)n2nc(-c3ccc(C(C)(C)C)cc3)c3ccccc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.48
ALDH1A1 P00352 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
RORC P51449 2/20 0.47
SLC9A1 P19634 1/20 0.45
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
NPSR1 Q6W5P4 2/20 0.43
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HSD11B1 P28845 2/20 0.43
PIK3CD O00329 1/20 0.42
PIK3CA P42336 1/20 0.42
PIK3CB P42338 1/20 0.42
PIK3CG P48736 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30302200 0.88 NR1H2 (0.53) HTTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL12253466 0.87 NR1H2 (0.56) HTTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL30302191 0.85 RORC (0.51) ALDH1A1MEN1KMT2ASMN1; SMN2RORC
SCHEMBL30302196 0.85 SLC9A1 (0.47) HTTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL30302195 0.83 RORC (0.47) HTTALDH1A1MEN1KMT2ARORC
SCHEMBL30302188 0.81 MAPT (0.47) HTTALDH1A1MEN1KMT2AHPGD
SCHEMBL24329855 0.78 SLC9A1 (0.44) HTTMEN1KMT2ARORCSLC9A1
SCHEMBL30302187 0.78 RORC (0.54) HTTALDH1A1MEN1KMT2AHPGD
SCHEMBL30302190 0.78 NR1H2 (0.53) HTTALDH1A1MEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL30611203 0.77 SLC9A1 (0.43) HTTMEN1KMT2ARORCSLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115928114-B Synthetic method of aromatic hydrocarbon pyrazole compound 淮北师范大学 2023-06-27 CN disclosed
CN-115928114-A Synthetic method of aromatic pyrazole compound 淮北师范大学 2023-04-07 CN disclosed