Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 6/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030385 | 1.00 | ALDH1A1 (0.50) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3030387 | 1.00 | ALDH1A1 (0.50) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3025149 | 0.79 | ALDH1A1 (0.60) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3025148 | 0.79 | ALDH1A1 (0.60) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3025150 | 0.79 | ALDH1A1 (0.60) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3040083 | 0.75 | ALDH1A1 (0.52) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3040080 | 0.75 | ALDH1A1 (0.52) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3040078 | 0.75 | ALDH1A1 (0.52) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14446276 | 0.74 | ALDH1A1 (0.70) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL10977644 | 0.74 | ALDH1A1 (0.54) | ALDH1A1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501658-B2 | Enantioselective reactions catalyzed by chiral triazolium salts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-06 | — | — | US | disclosed |
| US-20100210452-A1 | ENANTIOSELECTIVE REACTIONS CATALYZED BY CHIRAL TRIAZOLIUM SALTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210452-A1 | ENANTIOSELECTIVE REACTIONS CATALYZED BY CHIRAL TRIAZOLIUM SALTS | IDH1, MDM4, PCNA | ALDH1A1 1165/4885F2 3122/4885PRSS1 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.