Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10682761 | 0.83 | LMNA (0.53) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL10683204 | 0.82 | KMT2A (0.44) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL10681241 | 0.82 | CA2 (0.46) | ALDH1A1F2GAAMEN1KMT2A | |
| SCHEMBL10671764 | 0.82 | F2 (0.44) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1178745 | 0.76 | ALDH1A1 (0.52) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL19547285 | 0.75 | ALDH1A1 (0.88) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL19547283 | 0.75 | ALDH1A1 (0.88) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7310589 | 0.74 | F2 (0.56) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3030385 | 0.74 | ALDH1A1 (0.50) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3030388 | 0.74 | ALDH1A1 (0.50) | ALDH1A1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159012-A2 | Sulfonamidines, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1985-10-23 | — | — | EP | disclosed |