Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Spiroxamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Spiroxamine SCHEMBL20282 | 0.93 | PABPC1 (0.31) | — | |
| Spiroxamine SCHEMBL17335924 | 0.93 | PABPC1 (0.31) | — | |
| Spiroxamine SCHEMBL27795318 | 0.92 | PABPC1 (0.30) | — | |
| SCHEMBL19088354 | 0.83 | ADRA1A (0.32) | — | |
| SCHEMBL9543293 | 0.82 | — | — | |
| Spiroxamine SCHEMBL23302166 | 0.81 | — | — | |
| SCHEMBL1192491 | 0.80 | PABPC1 (0.32) | — | |
| SCHEMBL12532487 | 0.80 | PABPC1 (0.32) | — | |
| Spiroxamine SCHEMBL17335926 | 0.80 | — | — | |
| SCHEMBL9678064 | 0.79 | PABPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179518-A1 | Pesticidal Mixtures Comprising Cyanosulfoximine Compounds | BASF SE (DE) | 2014-06-26 | — | — | US | claimed |
| JP-2012500824-A | — | — | 2012-01-12 | — | — | JP | claimed |
| US-20110159107-A1 | Pesticidal Mixtures Comprising Isoxazoline Compounds II | BASF SE (DE) | 2011-06-30 | — | — | US | claimed |
| US-20110160054-A1 | Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram | BASF SE (DE) | 2011-06-30 | — | — | US | claimed |
| EP-2320741-A2 | PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM | BASF SE (DE) | 2011-05-18 | — | — | EP | claimed |
| US-20110105321-A1 | Pesticidal Mixtures Comprising Cyanosulfoximine Compounds | BASF SE (DE) | 2011-05-05 | — | — | US | claimed |
| WO-2010023171-A2 | PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM | BASF SE (DE) | 2010-03-04 | — | — | WO | claimed |
| US-20220168278-A1 | LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST | VIRBAC (FR) | 2022-06-02 | — | — | US | disclosed |
| EP-3927341-A1 | LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST | VIRBAC (FR) | 2021-12-29 | — | — | EP | disclosed |
| WO-2020201440-A1 | LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST | VIRBAC (FR) | 2020-10-08 | — | — | WO | disclosed |
| US-20140179518-A1 | Pesticidal Mixtures Comprising Cyanosulfoximine Compounds | BASF SE (DE) | 2014-06-26 | — | — | US | disclosed |
| US-8597688-B2 | Pesticidal mixtures comprising isoxazoline compounds II | BASF SE (DE) | 2013-12-03 | — | — | US | disclosed |
| US-20110159107-A1 | Pesticidal Mixtures Comprising Isoxazoline Compounds II | BASF SE (DE) | 2011-06-30 | — | — | US | disclosed |
| US-20110160054-A1 | Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram | BASF SE (DE) | 2011-06-30 | — | — | US | disclosed |
| EP-2317856-A1 | PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS II | BASF SE (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-20110105321-A1 | Pesticidal Mixtures Comprising Cyanosulfoximine Compounds | BASF SE (DE) | 2011-05-05 | — | — | US | disclosed |
| EP-2219456-A1 | PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS | BASF SE (DE) | 2010-08-25 | — | — | EP | disclosed |
| WO-2010003877-A1 | PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS II | BASF SE (DE) | 2010-01-14 | — | — | WO | disclosed |
| WO-2009062905-A1 | PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS | BASF SE (DE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009007233-A2 | PESTICIDAL MIXTURES COMPRISING SULFONAMIDES AND ONE OR MORE FUNGICIDES | BASF SE (DE) | 2009-01-15 | — | — | WO | disclosed |