Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042776 | 0.88 | SETD7 (0.45) | SETD7TP53GLAHPGDMAPT | |
| Hydrochloric Acid SCHEMBL3040538 | 0.84 | SETD7 (0.46) | SETD7TP53KDM4EALDH1A1GAA | |
| SCHEMBL3030798 | 0.81 | TP53 (0.60) | TP53THRBGLAKDM4EALDH1A1 | |
| SCHEMBL3132987 | 0.79 | SETD7 (0.46) | SETD7TP53THRBGLAKDM4E | |
| SCHEMBL3138906 | 0.76 | ROCK2 (0.45) | SETD7KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL3142605 | 0.76 | KDM4E (0.45) | SETD7TP53THRBGLAKDM4E | |
| SCHEMBL3042775 | 0.71 | ALDH1A1 (0.51) | SETD7TP53THRBGLAKDM4E | |
| SCHEMBL3034895 | 0.71 | SETD7 (0.53) | SETD7TP53ALDH1A1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL14693457 | 0.69 | SETD7 (0.43) | SETD7TP53THRBGLAKDM4E | |
| SCHEMBL11600017 | 0.69 | SETD7 (0.71) | SETD7TP53ALDH1A1MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243778-B1 | PIPERIDINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2014-10-29 | — | — | EP | disclosed |
| US-8377967-B2 | Piperidine derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20100331365-A1 | PIPERIDINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
| EP-2243778-A1 | PIPERIDINE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2010-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331365-A1 | PIPERIDINE DERIVATIVE | HRH4, HRH3, HRH2 | SETD7 1033/4885TP53 4621/4885THRB 2604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.