SCHEMBL3030893

SCHEMBL3030893

O=C(O)c1cc2ccc(OCc3ccccc3)cc2[nH]1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.80
HPGD P15428 3/20 0.80
KDM4E B2RXH2 2/20 0.80
HSD17B10 Q99714 2/20 0.80
ALDH1A1 P00352 2/20 0.80
CYP1A2 P05177 1/20 0.80
CYP2C9 P11712 1/20 0.80
FLT3 P36888 1/20 0.69
PDGFRB P09619 1/20 0.67
PDGFRA P16234 1/20 0.67
SRD5A1 P18405 1/20 0.62
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
RXFP1 Q9HBX9 1/20 0.54
MAPT P10636 1/20 0.54
DAO P14920 1/20 0.54
CFD P00746 1/20 0.54
ALOX5 P09917 1/20 0.54
ACHE P22303 1/20 0.53
MAOB P27338 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30920873 1.00 SRD5A2 (0.80) SRD5A2HPGDKDM4EHSD17B10ALDH1A1
SCHEMBL6087004 0.89 FLT3 (0.66) SRD5A2HPGDKDM4EHSD17B10ALDH1A1
SCHEMBL630515 0.89 SRD5A2 (1.00) SRD5A2HPGDKDM4EHSD17B10ALDH1A1
SCHEMBL8406972 0.87 FLT3 (0.70) SRD5A2HPGDKDM4EHSD17B10ALDH1A1
SCHEMBL3057182 0.85 FLT3 (0.64) SRD5A2HPGDKDM4EHSD17B10ALDH1A1
SCHEMBL10002831 0.84 FLT3 (0.60) SRD5A2HPGDKDM4EHSD17B10ALDH1A1
SCHEMBL4523117 0.84 HPGD (0.68) SRD5A2HPGDKDM4EHSD17B10ALDH1A1
SCHEMBL7174812 0.82 SRD5A2 (0.88) SRD5A2HPGDKDM4EHSD17B10ALDH1A1
SCHEMBL6542823 0.82 NR1H4 (0.56) SRD5A2HPGDKDM4EHSD17B10ALDH1A1
SCHEMBL4879379 0.81 PDGFRB (0.59) SRD5A2HPGDKDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103923765-A Detergent Composition For Process Of Manufacturing Semiconductors And Displays COWON INNOTECH INC 2014-07-16 CN claimed
EP-2149552-A1 5,6 substituted benzamide derivatives as modulators of EP2 receptors Bayer Schering Pharma AG (DE) 2010-02-03 EP claimed
CN-1275942-C Benzyloxy substituted indole compound and its analog and their production method and application UNIV FUDAN (CN) 2006-09-20 CN claimed
CN-1569834-A Benzyloxy substituted indole compound and its analog and their production method and application UNIV FUDAN (CN) 2005-01-26 CN claimed
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 EP disclosed
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2024-06-20 US disclosed
WO-2024081748-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2024-04-18 WO disclosed
US-9869027-B2 Cleaning composition and method of manufacturing metal wiring using the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-16 US disclosed
EP-2721011-B1 PROSTAGLANDIN RECEPTOR EP2 ANTAGONISTS, DERIVATIVES, COMPOSITIONS, AND USES RELATED THERETO UNIV EMORY (US) 2017-09-06 EP disclosed
US-20160230289-A1 CLEANING COMPOSITION AND METHOD OF MANUFACTURING METAL WIRING USING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2016-08-11 US disclosed
US-9340759-B2 Cleaning composition and method of manufacturing metal wiring using the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-05-17 US disclosed
US-20150136728-A1 CLEANING COMPOSITION AND METHOD OF MANUFACTURING METAL WIRING USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-05-21 US disclosed
US-6248772-B1 HYPOTENSIVE AGENTS; ANTIARRHYTHMIA AGENTS; ANTIDIABETIC AGENTS; ANTIPROLIFERATIVE AGENTS SUMITOMO PHARMACEUTICALS CO., LTD. (JP) 2001-06-19 US disclosed
US-6169107-B1 USEFUL FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY INCREASED SODIUM/PROTON (NA.SUP.+ /H.SUP.+) EXCHANGER ACTIVITY, FOR EXAMPLE, HYPERTENSION, ARRHYTHMIA, ANGINA PECTORIS, CARDIAC HYPERTROPHY, DIABETES MELLITUS SUMITOMO PHARMACEUTICAL CO., LTD. (JP) 2001-01-02 US disclosed
US-5866589-A Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds PHARMACIA & UPJOHN COMPANY (US) 1999-02-02 US disclosed
EP-0622356-B1 Indoloylguanidine derivatives as inhibitors of sodium-hydrogen exchange SUMITOMO PHARMA (JP) 1998-07-01 EP disclosed
EP-0797576-A1 ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS PHARMACIA & UPJOHN COMPANY (US) 1997-10-01 EP disclosed
WO-1996018628-A1 ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS PHARMACIA & UPJOHN COMPANY (US) 1996-06-20 WO disclosed
EP-0708091-A2 Indoloylguanidine derivatives SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1996-04-24 EP disclosed
EP-0622356-A1 Indoloylguanidine derivatives as inhibitors of sodium-hydrogen exchange SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1994-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF SLC6A19, SLC2A9, SLC6A3 SRD5A2 975/4885HPGD 2264/4885KDM4E 3995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.