Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 8/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850971 | 1.00 | TGFBR1 (0.51) | TGFBR1PIK3CDPIK3CAPI4KAPIK3CG | |
| SCHEMBL3829949 | 0.78 | MYC (0.59) | TGFBR1 | |
| SCHEMBL19638056 | 0.77 | TGFBR1 (0.48) | TGFBR1KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1449744 | 0.77 | CDC7 (0.58) | KDM4EGLAMAPTALDH1A1GAA | |
| SCHEMBL15993170 | 0.77 | KDR (0.41) | KDM4EGLANPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL20511964 | 0.76 | KDR (0.40) | KDM4EGLANPC1MAPTRAB9A | |
| SCHEMBL11796387 | 0.76 | TGFBR1 (0.56) | TGFBR1PIK3CDPIK3CAPI4KAPIK3CG | |
| SCHEMBL3737029 | 0.76 | TGFBR1 (0.55) | TGFBR1PIK3CDPIK3CAPI4KAPIK3CG | |
| SCHEMBL31361561 | 0.76 | TGFBR1 (0.55) | TGFBR1PIK3CDPIK3CAPI4KAPIK3CG | |
| SCHEMBL18230478 | 0.75 | CCR1 (0.49) | KDM4EMAPTALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198939-B | Modulators of adenosine A3 receptors | 帕罗生物制药有限公司 | 2023-03-28 | — | — | CN | disclosed |