Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.68 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.68 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.68 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13216055 | 0.93 | ABCC1 (0.86) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL7817206 | 0.92 | KDM4E (0.88) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL3032293 | 0.88 | KDM4E (0.80) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL7368284 | 0.86 | KDM4E (1.00) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL11452241 | 0.86 | ABCC1 (0.74) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL3017205 | 0.85 | KDM4E (0.76) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL3029762 | 0.85 | KDM4E (0.76) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL3022545 | 0.85 | ABCC1 (0.74) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL10895180 | 0.84 | CACNA1F (0.76) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL3027412 | 0.84 | ADORA3 (0.89) | ABCC1ALDH1A1KDM4ESMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483563-B | Preparation method and application of novel ionic beta-naphthoic aldehyde Schiff base zirconium complex | 山西医科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-110683984-A | Method for ultrasonically oxidizing hanster 1, 4-dihydropyridine derivative | 阜阳师范大学 | 2020-01-14 | — | — | CN | disclosed |
| US-20100216784-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | MULLAN MICHAEL J | 2010-08-26 | — | — | US | disclosed |
| US-20100216784-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | MULLAN MICHAEL J | 2010-08-26 | — | — | US | disclosed |
| US-20100215735-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | MULLAN MICHAEL J | 2010-08-26 | — | — | US | disclosed |
| US-20100215735-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | MULLAN MICHAEL J | 2010-08-26 | — | — | US | disclosed |
| US-20100216784-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | MULLAN MICHAEL J | 2010-08-26 | — | — | US | disclosed |
| US-20100215735-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | MULLAN MICHAEL J | 2010-08-26 | — | — | US | disclosed |
| US-20080058330-A1 | Compounds and Combinations Thereof for Inhibiting Beta-Amyloid Production and Methods of Use Thereof | ROSKAMP RESEARCH LLC (US) | 2008-03-06 | — | — | US | disclosed |
| US-20080058330-A1 | Compounds and Combinations Thereof for Inhibiting Beta-Amyloid Production and Methods of Use Thereof | ROSKAMP RESEARCH LLC (US) | 2008-03-06 | — | — | US | disclosed |
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-16 | — | — | US | disclosed |
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-09 | — | — | US | disclosed |
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-09 | — | — | US | disclosed |
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-09 | — | — | US | disclosed |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ALZHEIMER'S INSTITUTE OF AMERICA, INC. | 2007-02-15 | — | — | US | disclosed |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ALZHEIMER'S INSTITUTE OF AMERICA, INC. | 2007-02-15 | — | — | US | disclosed |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ALZHEIMER'S INSTITUTE OF AMERICA, INC. | 2007-02-15 | — | — | US | disclosed |
| US-20060188938-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ARCHER PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058330-A1 | Compounds and Combinations Thereof for Inhibiting Beta-Amyloid Production and Methods of Use Thereof | APP, PSEN1, PSEN2 | ABCC1 757/4885ALDH1A1 3749/4885KDM4E 4629/4885 |
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | ABCC1 401/4885ALDH1A1 3939/4885KDM4E 4759/4885 |
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | ABCC1 401/4885ALDH1A1 3939/4885KDM4E 4759/4885 |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | ABCC1 401/4885ALDH1A1 3939/4885KDM4E 4759/4885 |
| US-20100216784-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | APP, PSEN1, PSEN2 | ABCC1 401/4885ALDH1A1 3939/4885KDM4E 4759/4885 |
| US-20060188938-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | ABCC1 401/4885ALDH1A1 3939/4885KDM4E 4759/4885 |
| US-20100215735-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | APP, PSEN1, PSEN2 | ABCC1 401/4885ALDH1A1 3939/4885KDM4E 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.