SCHEMBL3027412

SCHEMBL3027412

CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccccc1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 3/20 0.89
KDM4E B2RXH2 6/20 0.75
ALDH1A1 P00352 4/20 0.75
TSHR P16473 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
ABCC1 P33527 1/20 0.73
GAA P10253 2/20 0.71
HPGD P15428 2/20 0.71
HSD17B10 Q99714 2/20 0.71
LMNA P02545 1/20 0.71
CACNA1D Q01668 3/20 0.67
CACNA1F O60840 2/20 0.67
CACNA1S Q13698 2/20 0.67
CACNA1C Q13936 2/20 0.67
CACNA1B Q00975 1/20 0.64
CASP1 P29466 1/20 0.63
MEN1 O00255 1/20 0.63
MAPT P10636 1/20 0.63
XBP1 P17861 1/20 0.63
KMT2A Q03164 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29173863 0.95 ADORA3 (0.82) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2
SCHEMBL11860075 0.94 ADORA3 (0.80) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2
SCHEMBL20610477 0.94 ADORA3 (1.00) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2
SCHEMBL7817206 0.92 KDM4E (0.88) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2
SCHEMBL10684386 0.91 ADORA3 (0.75) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2
SCHEMBL1664685 0.89 ADORA3 (0.71) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2
SCHEMBL11524972 0.89 ADORA3 (0.71) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2
SCHEMBL7815344 0.88 ADORA3 (0.74) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2
SCHEMBL3010331 0.87 ADORA3 (0.70) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2
SCHEMBL3032293 0.87 KDM4E (0.80) ADORA3KDM4EALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119819362-A Photocatalyst for efficiently catalyzing and synthesizing halogenated aromatic hydrocarbon as well as preparation method and application thereof 中国石油大学(华东) 2025-04-15 CN claimed
CN-119819362-A Photocatalyst for efficiently catalyzing and synthesizing halogenated aromatic hydrocarbon as well as preparation method and application thereof 中国石油大学(华东) 2025-04-15 CN disclosed
US-20230382749-A1 PHOTODRIVEN TRANSFER HYDROGENATION OF N2 TO NH3 CALIFORNIA INST OF TECHN (US) 2023-11-30 US disclosed
CN-110483563-B Preparation method and application of novel ionic beta-naphthoic aldehyde Schiff base zirconium complex 山西医科大学 2021-12-28 CN disclosed
CN-110683984-A Method for ultrasonically oxidizing hanster 1, 4-dihydropyridine derivative 阜阳师范大学 2020-01-14 CN disclosed
US-20150376224-A1 USE OF COMPOSITIONS OBTAINED BY CALCINING PARTICULAR METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CATALYTICAL REACTIONS UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) 2015-12-31 US disclosed
US-20150376224-A1 USE OF COMPOSITIONS OBTAINED BY CALCINING PARTICULAR METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CATALYTICAL REACTIONS UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) 2015-12-31 US disclosed
US-20150011749-A1 USE OF CERTAIN METAL-ACCUMULATING PLANTS FOR THE PERFORMANCE OF ORGANIC CHEMISTRY REACTIONS UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) 2015-01-08 US disclosed
WO-2014128283-A1 USE OF COMPOSITIONS OBTAINED BY CALCINING PARTICULAR METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CATALYTICAL REACTIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2014-08-28 WO disclosed
EP-2769765-A1 Use of compositions obtained by calcing particular metal-accumulating plants for implementing catalytical reactions Centre National De La Recherche Scientifique (FR) 2014-08-27 EP disclosed
US-4492703-A HYPOTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1985-01-08 US disclosed
US-4304914-A CARDIOTONIC AGENTS, HYPOTENSIVE AGENTS USV PHARMACEUTICAL CORPORATION (US) 1981-12-08 US disclosed
US-4248873-A Nitro-substituted 1,4-dihydropyridines, processes for _their production and their medicinal use BAYER AKTIENGESELLSCHAFT (DE) 1981-02-03 US disclosed
US-4188395-A 1,4-Dihydropyridine derivatives substituted in the 2 position, and their use as medicaments BAYER AKTIENGESELLSCHAFT (DE) 1980-02-12 US disclosed
US-4179500-A 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments BAYER AKTIENGESELLSCHAFT (DE) 1979-12-18 US disclosed
US-4177278-A 2-Alkyleneaminodihydropyridines compounds, their production and their medicinal use BAYER AKTIENGESELLSCHAFT (DE) 1979-12-04 US disclosed
US-4166855-A 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ester, and its use as a peripheral vasodilator BAYER AKTIENGESELLSCHAFT (DE) 1979-09-04 US disclosed
US-4162321-A Sulphur-containing amino-dihydropyridines, and their use as medicants BAYER AKTIENGESELLSCHAFT (DE) 1979-07-24 US disclosed
US-4146627-A AMINOALKYLIDEAMINO-1,4-DIHYDROPYRIDINES AND THEIR USE AS MEDICAMENTS BAYER AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed
US-3956341-A 1,3,5-Tricarbo-1,4-dihydropyridines SMITHKLINE CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011749-A1 USE OF CERTAIN METAL-ACCUMULATING PLANTS FOR THE PERFORMANCE OF ORGANIC CHEMISTRY REACTIONS ME1, OSGEP, AGL ADORA3 2464/4885KDM4E 3624/4885ALDH1A1 912/4885
US-20150376224-A1 USE OF COMPOSITIONS OBTAINED BY CALCINING PARTICULAR METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CATALYTICAL REACTIONS CACYBP, PPA1, IPMK ADORA3 4165/4885KDM4E 4437/4885ALDH1A1 3184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.